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differential causes medications nephrology rhabdomyolysis sideeffects aclf anesthesia anesthesiology antipsychotics checklist chronic cirrhosis failure firstgeneration gastroenterology gravis hepatology hyperthermia injury
Medications causing Acute Kidney Injury (AKI) Prerenal: • Dehydration: Diuretics • Altered intrarenal autoregulation: ACEIs / ARBs,
sphincter tone: • Opiates ... decongestants) • Any drug ... #Medications #Drugs ... #pharmacology # ... differential #diagnosis
Neurological Side Effects of Antipsychotic Drugs Acute dystonia - Spasm of muscles of tongue, face, neck, back
Drugs Acute dystonia ... dose or change drug ... recognition and drug ... #Drugs #Medications ... #management
Vancomycin Associated Acute Kidney Injury • Drug induced acute kidney injury is generally defined as a
Kidney Injury • Drug ... induced acute kidney ... 24-72 hours of drug ... #Vancomycin #AKI ... #pharmacology #
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Hepatitis (AAH) Drug-Induced ... gastroenterology #management ... #diagnosis
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
Treatment depends ... anaphylaxis (→ 3-1) Drug ... induced: • Neuroleptic ... Anesthesia #Checklist #Diagnosis ... #Management #Workup
First Generation Anti-Psychotics: Mechanisms and Side Effects Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine ACh M1 antagonist - Block
irreversible • Drug ... induced Parkinsonism ... bradykinesia/akinesia • Acute ... #SideEffects #pharmacology ... #diagnosis #psychiatry
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
- Differential Diagnosis ... and Management ... Drugs (Statins), ... Dermatomyositis) AKI ... #causes #treatment
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... Framework and Management ... - Toxins - Drugs ... declines > ALT) • AKI ... + myoglobin AKI
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Penicillamine induced ... myasthenia Diagnosis ... aspiration and acute ... precipitated by: Drugs ... #management #neurology
5-Oxoprolinuria What is it: • Aka pyroglutamic acidosis, Intermediate in γ-glutamyl cycle • Amino acid transport and
What is it: • Aka ... • Concomitant acute ... diabetes • Other drugs ... Oxoprolinuria #diagnosis ... #management #treatment
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