30 results
Drugs affecting the cardiac action potential. The sharp rise in voltage ("0") corresponds to the influx
Drugs affecting ... to the sodium-channel ... repolarizing eflux of potassium ... #Pathophys #Pharmacology ... Antiarrhythmics #Classes
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Drugs that Impair ... Renal Potassium ... Decreased ENaC channel ... #Hyperkalemia #Pathophysiology ... #Pharmacology #
Antiarrhythmic Drugs

CLASS IA
 • Procainamide, Quinidine, Disopyramide
CLASS 1B
 • Lidocaine, Mexiletine
CLASS 2
 • Propranolol, Esmolol
CLASS 4
Antiarrhythmic Drugs ... CLASS IA • ... Disopyramide CLASS ... Adenosine, Magnesium, Potassium ... Classification #Pharmacology
Antiarrhythmic Medications - Vaughan Williams Classification - Summary Table
Class I agents - Sodium Channel Blockers⠀
Class II
agents - Sodium Channel ... III agents - Potassium ... Channel Blockers ... - Calcium Channels ... Summary #Table #pharmacology
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Classification: CLASS ... 1 - Sodium Channel ... 3 - Potassium Channel ... Vaughan #Williams #Pharmacology ... #pathophysiology
Potassium Channel Blockers - Medications
1. Cardiovascular Drugs
2. Psychiatric drugs
3. Other drugs
4. Synthetic opioids: Levomethadyl 
5. Opium
Potassium Channel ... Psychiatric drugs ... Other drugs 4. ... Organophosphates #Potassium ... Differential #Diagnosis #Pharmacology
Antiseizure Drugs 
Sodium Channel Blockers: Carbamazepine, Oxcarbazepine, Eslicarbazepine, Lamotrigine, Lacosamide, Phenytoin, fosphenytoin
Broad Spectrum: Valproate, Levetiracetam, Brivaracetam,
Antiseizure Drugs ... Sodium Channel ... Tiagabine, Vigabatrin Potassium ... Channel Opener: ... medications #epilepsy #pharmacology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... Classification: CLASS ... 3 - Potassium Channel ... Antiarrhythmics #Pharmacology ... #pathophysiology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... Heparin) • Sodium-channel ... differential #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Class III Antiarrhythmics - Potassium Channel Blockers - Indications and Side Effects
Amiodarone
 • Suppression of VT
Class III Antiarrhythmics ... - Potassium Channel ... a-flutter (when other drugs ... #Channel #Blockers ... #pharmacology #