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Aplastic Anemia Summary

 • Definition
 • Pathophysiology
 • DDx: AA vs Hypocellular MDS
 • Expectation
 •
Pathophysiology • DDx: AA
Amyloidosis Types - Comparison Table
Proteins depositing where they shouldn't
 • AL
 • TTR
 • AA

Julia Gips,
AL • TTR • AA
Approach to the A-a Gradient
A-a gradient = PAO2 - PaO2
A-a gradient = [FiO2 x (Patm -
of Chest Wall Elasticity ... UnremarkableLab #AA
Hypoxemia Differential Diagnosis Algorithm by A-a Gradient

Normal A-a Gradient:
 • ↓ Atmospheric pressure
 • Hypoventilation: CNS
Algorithm #pulmonary #Aa
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Dysfunction (pain, spasticity ... signs #symptoms #msk
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Hyperreflexia - Muscle spasticity ... Sensory ataxia or spasticity ... Hyperreflexia • Spasticity
Ely's Test for Rectus Femoris Spasticity

Ely's Test assesses rectus femoris spasticity.
With the patient prone, the examiner
Rectus Femoris Spasticity ... rectus femoris spasticity ... Rectus #Femoris #Spasticity ... video #sports #msk
Amyloidosis - Summary
Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Secondary amyloid A (AA ... nephropathy is common in AA ... light chain AA ... IL-1 & IL-6 → AA
The inverted or paradoxical triceps reflex consists of flexion of the elbow in response to percussion
an element of spasticity
Hand Arthritides - Differential Diagnosis by Location and Features

The Painful Hand!  Wish I would’ve thought
prior to my first MSK ... Diagnosis #Location #MSK