10 results
Sepsis - Diagnosis and Management
Life-threatening organ dysfunction caused by a dysregulated host response to infection
SEPTIC SHOCK
and Management ... Life-threatening organ dysfunction ... caused by a dysregulated ... Empiric broad spectrum ... Criteria #Diagnosis #Management
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
COMMON CAUSES + ... INITIAL MANAGEMENT ... • Start broad-spectrum ... ADVANCED MANAGEMENT ... #Diagnosis #Management
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
death -> end-organ dysfunction ... Inflammatory: infectious (sepsis ... O2 delivery • MI ... #diagnosis #management ... #differential #causes
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
death -> end-organ dysfunction ... Inflammatory: infectious (sepsis ... O2 delivery • MI ... #diagnosis #management ... #differential #causes
Shock Classification
Shock Definition: State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Classification ... END-ORGAN DYSFUNCTION ... of shock) • Septic ... Hemorrhagic → leading ... Types #diagnosis #management
Shock Types - Classification
State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Types - Classification ... END-ORGAN DYSFUNCTION ... 66% of shock) • Septic ... Hemorrhagic → leading ... types #diagnosis #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Eclampsia, Infection/Sepsis ... unclear, endothelial dysfunction ... the underlying cause ... with AEDs until cause ... Syndrome #diagnosis #management
Langerhans Cell Histiocytosis (LCH)

Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
various tissues, leading ... populations) CLINICAL SPECTRUM ... X-rays, CT, or MRI ... PET-CT / MRI: Staging ... Histiocytosis #Diagnosis #Management
Invasive Fungal Infection (IFI)

Invasive fungal infections are severe infections in which fungal pathogens invade normally sterile
(most frequent cause ... stay and broad-spectrum ... include fever, organ dysfunction ... Imaging studies (CT, MRI ... when feasible Management
DEMYELINATING DISEASES OF THE CENTRAL NERVOUS SYSTEM

What Are Demyelinating Diseases?
• Conditions that damage myelin, the protective
Neuromyelitis Optica Spectrum ... - Symptom management ... Neuromyelitis Optica Spectrum ... autoimmune/infectious causes ... bladder/bowel dysfunction