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diagnosis sepsis criticalcare cell cold criteria differential dry histiocytosis icu lactate langerhans lch map qsofa septic septicshock table warm wet
Systemic Inflammatory Response Syndrome (SIRS) • Non-specific (infections vs non-infectious) • ≥2 of the following: o Temp >38°C or <36°C o HR >90 bpm o RR
Response Syndrome (SIRS ... Septic Shock • ... >2 mmol/L Management ... hours) • Broad-spectrum ... #shock #lactate
Shock Types - Classification State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Types - Classification ... END-ORGAN DYSFUNCTION ... Hemorrhagic → leading ... #Classification ... #management #criticalcare
Shock Classification Shock Definition: State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Classification ... END-ORGAN DYSFUNCTION ... • Most common type ... #Classification ... #management #cold
Sepsis - Diagnosis and Management Life-threatening organ dysfunction caused by a dysregulated host response to infection SEPTIC SHOCK
Life-threatening organ dysfunction ... infection SEPTIC SHOCK ... Patients w/ septic shock ... Previously, we used SIRS ... Empiric broad spectrum
SEPSIS AND SEPTIC SHOCK DEFINITION AND PATHOPHYSIOLOGY • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
• 2001 SIRS: ... INITIAL MANAGEMENT ... • Start broad-spectrum ... ADVANCED MANAGEMENT ... #Diagnosis #Management
Langerhans Cell Histiocytosis (LCH) Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
Langerhans cells, a type ... various tissues, leading ... populations) CLINICAL SPECTRUM ... • Endocrine Dysfunction ... Histiocytosis #Diagnosis #Management
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