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diagnosis differential hematology agglutinin anemia autoantibodies causes cold disease diseases hemolytic icl idiopathic lymphocytopenia lymphopenia management myopathy myositis sjogrens syndrome
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
their Disease Associations ... common in SLE, autoimmune ... Celiac disease Anti-GBM ... diagnosis #table #rheumatology ... #antibodies
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
• Persistent CD4 ... occasions COMMON ASSOCIATIONS ... Autoimmune (Sjogren ... EBV. CMV. ... ICL #diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral infection, autoimmune ... hemolysis • C3↓ C4 ... - Mycoplasma, EBV ... CLL (older) • Autoimmune ... hemolytic #anemia #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
be any age) Autoimmune ... /aggregate) of CD4 ... Disease: • 10%-15% Pulmonary ... , INC risk PE, Pulmonary ... Sjogrens #Syndrome #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... RP-ILD), dermato-rheumatologic ... (also seen in association ... • ANA < 20 % IBM ... Myositis #Myopathy #rheumatology
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