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diagnosis differential reactions hypersensitivity management hematology allergic anemia definitions primarycare table treatment angioedema antibiotics antibody autoimmune blood clinicopathology comparison diabetes
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Hypersensitivity: Summary Type ... conjunctivitis Type ... thrombocytopenia, Autoimmune Hemolytic ... Graves' Disease Type ... #Types #Classification
Types of hypersensitivity reactions Type I - lgE-Mediated, Within I Hour (Anaphylaxis) Type II - IgG or IgM
reactions Type ... Hours to Days (Hemolytic ... Anemia) Type ... #Classification ... #Allergy #Diagnosis
Hemolysis Classification - Intrinsic and Extrinsic Causes Commentary: Another way to think of immune hemolysis would be
Hemolysis Classification ... and Extrinsic Causes ... autoimmune (most of the causes ... #Classification ... #Algorithm
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Antibody Autoimmune Hemolytic ... reticulocytes • Hemolysis ... Coombs • IgG type ... 2) LOOK FOR a cause ... Rituximab +++ 3 - Splenectomy
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... or during hemolytic ... #Classification ... Pathophysiology #Allergy
Angioedema - Classification Diagnosis and Treatment Types of Angioedema: • Acute allergic angioedema - Usually occurs with
Angioedema - Classification ... and Treatment Types ... cell-mediated in > 90% of cases ... #Angioedema #Classification ... #Types #Diagnosis
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... lgE causes mast-cell ... transfusion reaction, Haemolytic ... #allergy #table ... #classification
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
Definitions • Type ... reaction • Type ... cell surfaces causes ... causes development ... #Types #Classification
Penicillin Allergy Pathway for Antibiotic Prescription in Patients With Penicillin Allergy Mild Reaction - Itching, Minor rash
Maculopapular rash (mild type ... Use carbapenem Type ... Type II-IV HSR ... symptoms syndrome, Hemolytic ... #Prescription #algorithm
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... blood loss, Acute hemolysis ... Asplenia/post-splenectomy ... , Exercise, Allergic ... Differential #Diagnosis #Algorithm
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