75 results
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Thrombocytosis - Differential ... Diagnosis Platelet ... trauma) • Post-splenectomy ... Thrombocytosis #Differential ... Diagnosis #causes #Platelets
Idiopathic Thrombocytopenic Purpura 
Clinical:
 • Gingival 
 • Menorrhagia 
 • GI bleeding 
 • Intracranial
children) • Platelets ... extremely low platelet ... immunoglobulin • Splenectomy
Indications for Transfusion
Packed RBCs
 • Hgb <7 g/dL or hematocrit <21% in a patient with uncompromised
hemoglobinopathy Platelets ... Prophylactically for platelet ... not transfuse platelets ... Platelet transfusions ... Management #RBCs #Platelets
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
Inherited Qualitative Platelet ... Single isolated platelets ... without platelet ... failure Grey Platelet ... comparison #table #differential
Thromboelastography (TEG) based therapy and Management

If r time prolonged -> FFP
If MA low -> plts/cryoprecipitate (if
cryoprecipitate If platelets ... < 50 - > platelet ... transfusions If
Thromboelastography (TEG) Based Management
 - If R time prolonged -> FFP 
 - If MA low
cryoprecipitate - If platelets ... < 50 -> platelet ... transfusions
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... count and platelet ... 1 or Type 3) — differentiate ... • Platelet flow ... hematology #hemepath #differential
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Thrombocytosis - Elevated Platelet ... Count - Differential ... Diagnosis Algorithm ... Asplenia/post-splenectomy ... Thrombocytosis #Platelets
Indications for Transfusion of Platelets in Neonates

#Management #Peds #Pediatrics #Platelets #Transfusion #Plateletpheresis #Thresholds #NonBleeding #Surgery
Indications for Transfusion ... of Platelets in ... Peds #Pediatrics #Platelets ... #Transfusion #Plateletpheresis
PLATELETS Mnemonic for Causes of Thrombocytopenia

P - Platelet Disorders (DIC, ITP, TTP)
L - Leukemia, Lymphoma
A -
PLATELETS Mnemonic ... Thrombocytopenia P - Platelet ... Anemia T - Trauma, Transfusion ... S - Sepsis #PLATELETS ... Thrombocytopenia #Differential