273 results
Idiopathic Thrombocytopenic Purpura 
Clinical:
 • Gingival 
 • Menorrhagia 
 • GI bleeding 
 • Intracranial
Intracranial hemorrhage Management ... children) • Platelets ... extremely low platelet ... immunoglobulin • Splenectomy
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Differential Diagnosis Platelet ... trauma) • Post-splenectomy ... Diagnosis #causes #Platelets
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
Inherited Qualitative Platelet ... Single isolated platelets ... without platelet ... failure Grey Platelet ... Defects #comparison #table
Recommended Vaccinations for Asplenic Patients - Before and After Splenectomy

#Management #Asplenic #Asplenia #Vaccinations #PrimaryCare #Vaccines #Splenectomy
Before and After Splenectomy ... #Management # ... PrimaryCare #Vaccines #Splenectomy
Blood Product Components, Contents, Volume and Shelf Life

Whole blood (autologous or directed donations) - RBC and
WBC and platelets ... Hct 60% Platelet ... pheresis - Platelets ... Volume #Hematology #Management ... #Table
Thromboelastography (TEG) based therapy and Management

If r time prolonged -> FFP
If MA low -> plts/cryoprecipitate (if
based therapy and Management ... cryoprecipitate If platelets ... < 50 - > platelet ... Thromboelastography #TEG #Management
Thromboelastography (TEG) Based Management
 - If R time prolonged -> FFP 
 - If MA low
Thromboelastography (TEG) Based Management ... cryoprecipitate - If platelets ... < 50 -> platelet ... Thromboelastography #TEG #Management
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Thrombocytosis - Elevated Platelet ... Asplenia/post-splenectomy ... Thrombocytosis #Platelets
Thresholds for Transfusion of Platelets in Adults
Major surgery or invasive procedure, no active bleeding - 
≤
Transfusion of Platelets ... 100 (rarely) Stable ... nonbleeding - < 10 Stable ... procedure - < 20 #Management ... #Platelets #Transfusion
Indications for Transfusion
Packed RBCs
 • Hgb <7 g/dL or hematocrit <21% in a patient with uncompromised
hemoglobinopathy Platelets ... not transfuse platelets ... Platelet transfusions ... Indications #Thresholds #Management ... #RBCs #Platelets