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diagnosis management differential hematology algorithm clinical workup causes syndrome infectiousdiseases anemia microscopy neurology pathophysiology hepatology criticalcare microbiology nephrology pulmonary smear
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
↑ LDH • Anti-RBC ... type ± C3d • Blood ... Rituximab +++ 3 - Splenectomy ... diagnosis #management #treatment
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... RBC) Morphology ... disease, McLeod blood ... phenotype, Post-splenectomy ... Hemoglobinopathies, Post-splenectomy
Post-splenectomy blood smear demonstrating Howell-Jolly bodies and target cells. #Clinical #Pathology #BloodSmear #HowellJollyBodies #TargetCells #Splenectomy #Asplenic
Post-splenectomy ... blood smear demonstrating ... #TargetCells #Splenectomy
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm Blood ... / Normochromic RBCs ... TIBC, Hypochromic RBCs ... Decreased RBC ... Disorder • RBC
Blood Product Components, Contents, Volume and Shelf Life Whole blood (autologous or directed donations) - RBC and
Blood Product Components ... Life Whole blood ... directed donations) - RBC ... Hct 35%. 450mL blood ... plasma, a few RBC
Common RBC Inclusions and Associations • Howell Jolly Bodies: Hyposplenism, Asplenism, Severe hemolytic anemia • Heinz
Common RBC Inclusions ... Hemolytic anemia, Post-splenectomy ... Sickle cell, MDS #RBC
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... RBC) Morphology ... intoxication, Post-splenectomy ... coagulopathy (DIC) #RBC
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
individual’s red blood ... cells (RBCs or ... serum due to the RBCs ... Clinical #Path #Blood ... Smear #Microscopy #RBC
ABO Blood Types and Transfusion Compatibility Table A Blood Type: • RBC Antigens: A • Antibodies: Anti-B
ABO Blood Types ... Type: • RBC Antigens ... Type: • RBC Antigens ... Type: • RBC Antigens ... Type: • RBC Antigens
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
individual’s red blood ... cells (RBCs or ... serum due to the RBCs ... Clinical #Path #Blood ... Smear #Microscopy #RBC
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