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sle erythematosus hematology syndrome systemic activation arteritis bacterial blood comparison degenerative dermatology disease fungal gca giantcell hcq hepatology hydroxychloroquine igg4
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Initial screening test ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
[HCQI reflects long-term ... if < 200ng/mL Best ... Measurement #SLE #rheumatology ... pharmacology #levels #lupus ... #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... • Malar rash - spares ... Erythematosus #Diagnosis ... #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
rash) • Heart, lung ... Liver function tests ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
biliary, renal, lung ... PET-CT Imaging (→ Diagnostic ... specific laboratory tests ... #management #phenotypes ... workup #treatment #rheumatology
Spontaneous Bacterial Peritonitis (SBP) - Diagnosis and Management Ascites PMN > 250/mm3 ? Nosocomial or hospital acquired. Recent
Peritonitis (SBP) - Diagnosis ... prophylaxis - Best ... evidence: long-term ... Upper Gl bleeding: Short-term ... Peritonitis #SBP #Diagnosis
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
nociceptors -> Pain with rest ... Rheumatoid arthritis, Lupus ... commonly affects the knee ... > Stiffness is short-lived ... JointDisease #JointPain #Diagnosis
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... the “Chewing gum test ... day, followed by long ... them, but urgent rheumatology ... #Management
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
anterior chest wall, parts ... • A clinical diagnosis ... blockers had the best ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
indirect Coombs test ... Related Acute Lung ... #Transfusions #diagnosis ... #management #hematology
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