12 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Initial screening test ... severe disease Treatment ... Hydroxychloroquine *Short ... Summary #diagnosis #rheumatology ... #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
to local skin injury ... ) • Neurologic ... Arthritis, AS Treatment ... #diagnosis #management ... signs #symptoms #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
) Clinical Manifestations ... Demyelinating Syndrome ... #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
rheumatoid arthritis, SLE ... Bedside: ice pack test ... /Edrophonium test ... Gravis #diagnosis #management ... #neurology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... erythematosus [SLE ... Liver function tests ... Treatment: • Corticosteroids ... #Management #Hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
complex → plt activation ... Diagnosis: • Clinical ... : Confirmatory test ... ↑Se/Sp but very ... #Treatment #Hematology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Excessive activation ... Transverse Myelitis - Clinical ... Presentation: Injury ... negative, MOG-IgG test ... #neurology #differential
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... patients with clinically ... stimulation Clinical ... sclerosis #diagnosis #management ... #neurology #treatment
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... Diagnosis: • A clinical ... and lower jaw Treatment ... #Rheumatology # ... diagnosis #management
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
Crisis (SRC) Clinical ... ) Acute kidney injury ... endothelial cell activation ... Renal #Crisis #rheumatology ... #management