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Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Idiosyncratic Drug-induced ... #DILI #Drug #induced ... #gastroenterology ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... Hepatitis (AAH) Drug-Induced ... Failure #Cirrhosis #Hepatology ... #gastroenterology ... #management #diagnosis
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
diagnosis and initial management ... HIT laboratory tests ... and to adjust treatment ... #Hematology #HIT ... #Heparin #Induced
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Heparin Induced ... approach for post-test ... : Confirmatory test ... #HIT #Heparin #Induced ... #Treatment #Hematology
Irritable Bowel Syndrome (IBS) - Management
Global IBS Symptoms:
  - Limited trial low FODMAP diet
Syndrome (IBS) - Management ... and Hepatology ... Bowel #Syndrome #Management ... #gastroenterology ... #treatment
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Diagnosis and Management ... • Shear stress-induced ... Syndrome #Diagnosis #Management ... #treatment #hematology
Eosinophilic Gastroenteritis: Treatment Options Based on Severity of the Disease
Mild:
 • Trial of PPI
 • Trial
Gastroenteritis: Treatment ... Concern for HES: • Hematology ... Gastroenteritis #Treatment ... #management #gastroenterology
Alcoholic Hepatitis - Management Algorithm
1. Severity assessed not only by MDF (>32) but also by MELD
Alcoholic Hepatitis - Management ... only increase short-term ... Alcoholic #Hepatitis #Management ... #Algorithm #treatment ... #hepatology
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary
Diagnosis:
 • Use a positive diagnostic strategy with
Diagnosis and Management ... for diagnosis Treatment ... and Hepatology ... #gastroenterology ... #treatment
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Treatment of Thrombotic ... HUS) Treatment ... PLEX and RTX • Short-term ... Thrombocytopenic #Purpura #management ... #hematology