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Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
the Skin - Differential ... racemosa, Digital ulceration ... - GPA Cutaneous ... Disease • Cogan syndrome ... #skin #dermatology
Skin Ulcers of the Lower Legs / Feet - Differential Diagnosis Algorithm
Physical:
• Pressure
• Trauma
• Radiation
Vascular:
• Arterial
Skin Ulcers of the ... insufficiency • Vasculitis ... Neoplastic: • Squamous ... #Feet #Ulcers #ulcerative ... #skinrash #dermatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... Bullae/Blisters • Ulceration ... reticularis Differential ... • Goodpasture syndrome ... • Giant cell arteritis
Skin Ulcers by Etiology - Differential Diagnosis Algorithm
Physical:
 • Trauma
 • Pressure
 • Radiation
Vascular:
 • Arterial
Skin Ulcers by Etiology ... insufficiency • Vasculitis ... Neoplastic: • Squamous ... Cryptococcosis #Ulcers #ulcerative ... #skinrash #dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... > PR3 60% • GPA ... • Cogan Syndrome ... episcleritis as well ... • ANCA (Dx: GPA
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... (Giant Cell Arteritis ... Multinucleated giant cells ... #Differential #
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Wilson's disease Pulmonary ... Spondyloarthropathies, SLE • Pulmonary ... Lyme disease, Vasculitis ... Scleroderma Thickened skin ... #joint #pain #differential
Highlighted Conditions With Arteritis or Periarteritis of the Coronaries
Takayasu's arteritis:
 - Onset < 40 yrs
 -
pulse/BP Giant cell ... Polyarteritis nodosa: - Skin ... sinusitis - pulmonary ... genital Sores - Ulceration ... Coronaries #Arteritis #Differential
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Lymphoma (HCV) • CLL ... Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... Autoimmunity: • -MM/WM: Vasculitis ... #Monoclonal #Differential