13 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Cell Disease Vaso-occlusive ... Generally affects long ... #diagnosis #causes ... #hematology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pain Eyes ... • Interstitial lung ... Scleroderma Thickened skin ... #pain #differential ... #diagnosis #rheumatology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
/white cell casts ... pancreatitis), joints ... plexus, or sclera), lungs ... effusion), mouth (ulcers ... nose (epistaxis), skin
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... surfaces of the joints ... burning sensation or pain ... syndrome • Giant cell ... #rheumatology
Ear Pain (Otalgia) - Differential Diagnosis Framework

Primary Otalgia 
 - Pain that originates from the ear
Cholesteatoma • Basal/squamous ... cell CA • Melanoma ... Temporomandibular joint ... Oral aphthous ulcers ... subdural hematoma, lung
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Milk • Food products ... status NTM Cause ... Advanced HIV (CD4 cell ... diarrhea, abdominal pain ... NTM #Infections #differential
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Multinucleated giant cells ... vesicular eruption • Joints ... tract, and often causes ... Palpable purpura, joint ... #Diagnosis #Rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
sensitivity • Painful ulcers ... thrombophlebitis, pulmonary ... cryoglobulins • Negative causes ... #rheumatology # ... hematology
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
in HIV - Differential ... • Risk: Can produce ... • Oral mucosal ulcers ... factor • May cause ... Infections #HIV #AIDS #pulmonary
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... livedo reticularis, ulcers ... vesicular eruption - Joints ... genital aphthous ulcers ... #diagnosis #rheumatology