17 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Cell Disease Vaso-occlusive ... Generally affects long ... #diagnosis #causes ... #hematology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
/white cell casts ... pancreatitis), joints ... heart disease, ear ... effusion), mouth (ulcers ... nose (epistaxis), skin
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pain Eyes ... Inflammation of ear ... Scleroderma Thickened skin ... #pain #differential ... #diagnosis #rheumatology
Ear Pain (Otalgia) - Differential Diagnosis Framework

Primary Otalgia 
 - Pain that originates from the ear
Ear Pain (Otalgia ... cell CA • Melanoma ... Temporomandibular joint ... Oral aphthous ulcers ... subdural hematoma, lung
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... surfaces of the joints ... syndrome • Giant cell ... #rash #diagnosis ... #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
CRP GCA (Giant Cell ... , mucositis • Rash ... Recurrent middle ear ... tract, and often causes ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... vesicular eruption - Joints ... mucositis - Rash ... as inner ear disease ... #diagnosis #rheumatology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
interphalangeal joints ... CD4+ and CD8+ T cell ... anti-NXP2 Abs Lung ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... permanent alopecia Differential ... Arthritis: • Joint ... pain • Swan neck ... #Rheumatology
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... (buruli ulcer) ... Advanced HIV (CD4 cell ... diarrhea, abdominal pain ... NTM #Infections #differential