10 results
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
• Interstitial lung ... • Shrinking lung ... Scleroderma Thickened skin ... #differential # ... diagnosis #rheumatology
Ear Pain (Otalgia) - Differential Diagnosis Framework

Primary Otalgia 
 - Pain that originates from the ear
) - Differential ... Cholesteatoma • Basal/squamous ... cell CA • Melanoma ... Oral aphthous ulcers ... subdural hematoma, lung
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... burning sensation or pain ... reticularis Differential ... • Goodpasture syndrome ... • Giant cell arteritis
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... : • Syndrome of ... Advanced HIV (CD4 cell ... diarrhea, abdominal pain ... #differential #
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... -> AML: Blast crises ... • Tumor lysis syndrome ... -> Invade Skin: ... #Leukemia #Hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Multinucleated giant cells ... tract: Abdominal pain ... MPO > PR3 60/ GPA ... tract, and often causes ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... livedo reticularis, ulcers ... genital aphthous ulcers ... to exclude are infections ... #diagnosis #rheumatology
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Lung Infections ... in HIV - Differential ... • Oral mucosal ulcers ... factor • May cause ... #AIDS #pulmonary
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
gammopathy, and skin ... changes (POEMS syndrome ... ovarian tumors, lung ... gastric tumors • Hematology ... #diagnosis #hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Malignancy • Infections ... sensitivity • Painful ulcers ... thrombophlebitis, pulmonary ... Antiphospholipid syndrome ... #hematology