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diagnosis management activetb latenttb tb tuberculosis abscess biliary bone cholangitis cirrhosis classification disease hemophagocytic hepatology hlh hodgkins joint lung lymphohistiocytosis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... +++ (Plt, Hb), Hepatic ... ↑ sIL-2R >2400 Ul ... Drugs, Unknown cause ... Treatment: •
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
without other cause ... fluid balance, and CXR ... Transfusion #Reactions #hematology ... #diagnosis #comparison ... #table
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Immunohistochemical studies (to differentiate ... Treatment • Early ... Stage (Favorable ... • Early Stage ... classification #hematology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... dx and stage ... Osteomyelitis / Septic ... • Differentiate ... #hematology
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
• Most common cause ... Lung Abscess Pathophysiology ... Blood cultures • CXR ... early disease) • CXR ... shows a small, stable
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... bile ducts Differential ... Endocrinopathy, Lymphoma ... malignancies, Hepatic
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Sarcoidosis • Lymphoma ... Lung cancer • Septic ... and Culture • CXR ... disease • Check CXR
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Sarcoidosis • Lymphoma ... Lung cancer • Septic ... and Culture • CXR ... disease • Check CXR
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