4 results
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
Januvia) - Once/day tablet ... Onglyza) - Once/day tablet ... Tradjenta) - Once/day tablet ... not definitively cause ... Summary #DM2 #diabetes
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
and Management Summary ... • Most common cause ... pneumonia • DM ... antibiotics once stable ... shows a small, stable
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
↑ sIL-2R >2400 Ul ... Treatment: • ... Anti-infectious, chemotherapy ... Anti-IFN-y and JAK inhibitors ... #summary #rheumatology
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity
Anthracyclines cause cardiomyopathy:
 ✖ Reduction in left ventricular ejection fraction
Anthracyclines cause ... HER2 agents cause ... ) and initiate treatment ... cardiology #oncology #pharmacology ... #toxicity #chemotherapy