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Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Evaluation and Management ... of Sickle Cell Crises ... #Diagnosis #Management ... #Hematology #SickleCell ... Manifestations #Workup
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE) - Diagnosis ... • Immunologic Workup ... Positive in 60-80% of cases ... Erythematosus #Diagnosis ... #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... Discontinuation of causal ... • Immunologic Workup ... #rheumatology # ... diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... ↑ sIL-2R >2400 Ul ... Drugs, Unknown cause ... #management #treatment ... #summary #rheumatology
Increased Airway Pressure - Guidelines for Crises in Anaesthesia

Using these steps from start to end should
should identify any cause ... surgery related cause ... If circulation unstable ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia
• Unexplained hypotension
• Unexplained bronchospasm (wheeze may be absent
arrest where other causes ... as a possible cause ... as patient is stable ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Mains Electricity Failure - Guidelines for Crises in Anaesthesia
Unexpected total power failure is rare and unpredictable.
Guidelines for Crises ... until patient is stable ... Guidelines for crises ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma Workup ... lymph node biopsy (diagnostic ... Hodgkins #lymphoma #diagnosis ... classification #hematology ... #oncology #management
High Central Neuraxial Block - Guidelines for Crises in Anaesthesia
• Can occur with deliberate or accidental
Guidelines for Crises ... Consider other causes ... ongoing care in a suitable ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... and Management ... reabsorption) Workup ... only if no clear cause ... Elimination (see Table