14 results
Anti-infective stewardship, including tips for using anti-infectives wisely, criteria for stepdown from IV to PO dosage
for using anti-infectives ... IV to PO anti-infectives ... #pharmacology #antibiotics ... #medications #table ... #treatment #drugs
Antibiotic classification refers to the categorization of antibiotics based on their chemical structure, mechanism of action,
drugs that are used ... treat bacterial infections ... Imagine treatments ... #Antibiotics #pharmacology ... classification #table
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
↑ sIL-2R >2400 Ul ... +: Virus (EBV, CMV ... or biologics (CMV ... immune deficiency, Drugs ... Treatment: • Etiological
IDSA Recommendations for Treating Cytomegalovirus Infections in HIV-AIDS
Preventing CMV Disease:
 • CMV end-organ disease is best
intraocular levels of drug ... control of the infection ... until steady state ... opportunistic #infections ... #HIVAIDS #pharmacology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
polymicrobial infection ... • Most common cause ... once stable - ... Cavitation > 6 cm ... shows a small, stable
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... - Cytotoxic drugs ... - β-lactam antibiotics ... - EBV - CMV ... aplastic anemia Treatment
Treatment Options for Helicobacter Pylori and Peptic Ulcer Disease

Active Helicobacter pylori—associated ulcer
1. Treat with anti—H pylori
is large (> I cm ... completion of antibiotic ... Consider other causes ... the preferred drugs ... #Management #Pharmacology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
• A state of hyperinflammatory ... superinfection, drug ... keratitis, iritis • CMV ... unintentional weight loss, nausea ... /drug resistance
Sulfonamides - Antibiotics Class Overview

BACTRIM/SEPTRA (TMP/SMX) - inhibit sequential steps in Folate synthesis --> bacteriostatic

Spectrum: Wide
Sulfonamides - Antibiotics ... Notable highlights ... including PCP PNA (drug ... choice, both for treatment ... #Pharmacology #Antibiotics
IDSA Recommendations for Treating Mycobacterium Tuberculosis Infection and Disease in HIV-AIDS
Treating LTBI (to prevent TB disease)
Indications:
Mycobacterium Tuberculosis Infection ... a person with infectious ... Please refer to the table ... opportunistic #infections ... #HIVAIDS #pharmacology