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rheumatology management differential classification druginduced vasculitis alopecia ana antibodies antineutrophil antinuclear antiphospholipid apls arthritis comparison complications cryoglobulinemia cryoglobulins dermatology dil
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antibody) and ANCA ... ) • Systemic lupus ... in drug-induced SLE ... Polyangiitis (Churg-Strauss ... #antibodies #diagnosis
Algorithm for the Evaluation and Management of Sickle Cell Crises Clinical Manifestations and Management #Diagnosis #Management #Hematology #SickleCell
Evaluation and ... Management #Diagnosis ... #Management #Hematology ... Manifestations #Workup ... #Algorithm #Ddxof
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... • Immunologic Workup ... Positive in 60-80% of cases ... • Evolution: ... Erythematosus #Diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... Discontinuation of causal ... • Immunologic Workup ... #table #rheumatology ... #diagnosis #management
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Complement: Post-strep ... GN, Lupus Nephritis ... #differential #diagnosis ... #algorithm #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... (e.g., SLE), anti-phospholipid ... - Bone marrow evaluation ... #Causes #Workup
Serious Bacterial Illness (SBI): 1) UTI and pyelonephritis Most common cause of SBI Accounts for 3-8% of uncharacterized fevers Female
pyelonephritis Most common cause ... Consider BCx, CSF evaluation ... of respiratory distress ... suggested if: - ANC ... SeriousBacterialIllness #Ddxof
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... (to support a diagnosis ... Arthritis #laboratory #workup ... #diagnosis #testing
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
- Differential Diagnosis ... Disease: Discoid lupus ... Scarring Alopecia: Lupus ... • Laboratory evaluation ... DHEAS) • ANA
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... DDX: • ANCA (Antineutrophil ... cytoplasmic antibody ... (e.g. systemic lupus
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