28 results
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
40 ml/min A - Anemia ... focal lesions on MRI ... Causes of false- ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... (CVID, WAS), (neurologic ... changes), high MCV anemia ... #Diagnosis #Causes ... #Workup #hematology
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
Diagnosis Framework ... ILD, OSA, pHTN, Anemia ... Rhabdomyolysis, Critical ... #Diagnosis #causes ... #neurology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... Clinical Presentation ... and petechiae Causes ... #oncology #hematology ... #diagnosis #management
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Significance (MGUS) - Differential ... Diagnosis Neurologic-Centered ... #Diagnosis #hematology ... #oncology
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
fatigue despite clinical ... Receptor (sTfR) to differentiate ... active IBD and/or stress ... /other causes • ... IBD #Algorithm #diagnosis
Etiologies of Folate Deficiency
 • Decreased dietary intake - uncommon in this era
 • Increased requirements
have hemolytic anemia ... folate that can cause ... mobilize folate stores ... deficiency #FolicAcid #differential ... #diagnosis #hematology
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
workup 1) Clinical ... MRI, iADL scale, ... Alzheimer - 1st cause ... - Progressive amnesia ... MNCD #Dementia #Differential
Focal Periphyseal Edema (FOPE lesion) - MSK Radiology
Imaging Findings:
 • Arrows identifying the characteristic edema-like signal
increased local stress ... repeated follow-up MRI ... (save $$) Differential ... diagnosis: • Salter ... #mri #clinical
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
Creatine Kinase - Causes ... mycoplasma, staph, strep ... immobility • Critical ... #Elevated #CK #differential ... #diagnosis #rhabdomyolysis