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Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Evaluation and Management ... of Sickle Cell Crises ... Clinical Manifestations ... and Management ... #Hematology #SickleCell
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
decades of life Causes ... and clinical associations ... trigger - Direct skin ... - Ice cube test ... Urticaria #diagnosis #rheumatology
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Capitis - Skin ... disease • Pull test ... Examine the entire skin ... texture at bald spots ... Differential #Diagnosis #dermatology
Iron Deficiency Anemia (IDA)
Tests:
 • MCV/RBC - RBC ↓ in proportion to the ↓ in hemoglobin
Anemia (IDA) Tests ... total body iron stores ... Fe #diagnosis #hematology
Diagnosing Vitamin B12 and/or Folate Deficiency

It turns out that simply measuring serum levels of B12 or
with low B12 stores ... normal tissue stores ... the first line tests ... tissue folate stores ... Diagnosis #Nutrition #Hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... GPA causes disease ... Rarely dominate the clinical ... vasculitis #Dermatologic ... rash #diagnosis #rheumatology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
arterial thrombosis, skin ... Diagnosis: • Clinical ... approach for post-test ... : Confirmatory test ... #Treatment #Hematology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Initial screening test ... Associated with skin ... Hydroxychloroquine *Short ... Summary #diagnosis #rheumatology ... #management
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
characterized by extensive skin ... Edema in 70% of cases ... Skin involvement ... #Syndrome #dermatology ... #diagnosis #management
Vibrio Vulnificus skin infection
Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. 
Vibrio vulnificus part of
Vibrio Vulnificus skin ... marine microbiota & causes ... cellulitis w/ black spots ... rash #cellulitis #dermatology ... #legs #clinical