43 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Complement: Post-strep ... diagnosis #algorithm #rheumatology
Diagnosing Vitamin B12 and/or Folate Deficiency

It turns out that simply measuring serum levels of B12 or
with low B12 stores ... normal tissue stores ... the first line tests ... tissue folate stores ... Diagnosis #Nutrition #Hematology
Iron Deficiency Anemia (IDA)
Tests:
 • MCV/RBC - RBC ↓ in proportion to the ↓ in hemoglobin
Anemia (IDA) Tests ... total body iron stores ... Fe #diagnosis #hematology
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
if < 200ng/mL Best ... suspected) • In case ... • Special cases ... Measurement #SLE #rheumatology ... levels #lupus #management
Posterior Cruciate Ligament (PCL) Injury: Pathogenesis and Clinical Findings
Classification of PCL Iniuries
 • Partial: Translation <
Some sort of end ... Varus & Valgus Stress ... Varus & Valgus Stress ... #Injury #MSK #Sports ... #pathophysiology
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Lithium • Stress ... disease • Pull test ... Scaling, pustules, crusts ... texture at bald spots ... Initial Laboratory Tests
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Initial screening test ... Hydroxychloroquine *Short ... Summary #diagnosis #rheumatology ... #management
In ARDS, we know that the lungs are so diffusely injured that the remaining total area
Likewise, stress ... is likely the best ... and promote Lung rest ... #pathophysiology ... #diagnosis #management
Etiologies of Folate Deficiency
 • Decreased dietary intake - uncommon in this era
 • Increased requirements
folate that can cause ... mobilize folate stores ... depleted tissue stores ... differential #diagnosis #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Diagnosis and Management ... ♀, ↑Age, ESRD Pathophysiology ... approach for post-test ... : Confirmatory test ... #Treatment #Hematology