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diagnosis amiodarone apml capillary clarksons differential differentiation disease diuresis diuretics excretion hematology induced leak lung medications nephrology oncology pharmacology polychondritis
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... Renal Syndromes ... #Renal #Syndromes ... differential #diagnosis #management ... #treatment
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... Anaphylaxis, Acute Renal ... APML #diagnosis #management
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Agents Regulating Renal ... irrigation • Management ... Torsemide) • Acute pulmonary ... Kidney stones caused ... Tolvaptan) • Treatment
Clarkson’s Disease - Capillary leak syndrome Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... 150 published cases ... filling +++ (risk of pulmonary ... #diagnosis #management ... #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
, INC risk PE, Pulmonary ... Distal (Type I) renal ... Adenocarcinoma Treatment ... #Rheumatology # ... Diagnosis #Management
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
starting amiodarone treatment ... acute respiratory distress ... syndrome) is rare ... macrophages Treatment ... #diagnosis #management
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
hearing loss, nausea ... Heart failure • Renal ... affected tissue Treatment ... Polychondritis #rheumatology ... #diagnosis #management
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