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diagnosis oncology differentiation emergencies evaluation hematology hemeonc management oncologic perioperative preop preoperative stratification
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Attempt if high risk ... Subacute-Acute: • Common: fever ... Imaging: CXR- pulmonary ... sepsis), PE, DAH, CHF
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
or family - Ever ... murmur 3/6) - Pulmonary ... disease b) CHF ... event, follow ACC algorithm ... one post op Cardiology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
: - Fever + ANC ... mg/dL or > 25 % rise ... interventional radiology ... (~20 %) and APL ... renal failure, pulmonary
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