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diagnosis differential vasculitis autoimmune systemic workup behcet chronic classification cll disease erythematosus examination hematology henochscholeinpurpura hsp iga infant leukemia lupus
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
less systemic symptoms ... heliotrope rash, Shaw sign ... , holster sign, ... anti-synthetase syndrome ... #diagnosis #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
elbows/wrists and knees ... skin thickening Signs ... acro-osteolysis, myositis ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Demyelinating syndromes ... Glomerulonephritis Myositis ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
meningitis), MCC CNS symptoms ... Positive pathergy test ... is a skin prick test ... diagnosis #management #signs ... #symptoms #rheumatology
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
virus or Group A Strep ... nephrotic/nephritic syndrome ... arthritis (especially knees ... Pathophysiology #Diagnosis #Signs ... #Symptoms
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
adults in the west ... with no early symptoms ... Physical Exam/Signs ... • Richter’s Syndrome ... leukemia • Sezary syndrome
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Conjunctivitis, mucositis ... Presentation - Systemic Symptoms ... purpura: strong sign ... retinopathy Lab Tests ... differential #diagnosis #rheumatology
Newborn Infant - Routine Examination Birthweight, gestational age and birthweight percentile are noted. General observation Of the baby's
is also a late sign ... assessment, is best ... are observed for signs ... of respiratory distress ... Newborn #Infant #PhysicalExam
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Diagnostic Tests ... RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... #Myopathy #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... Conjunctivitis, mucositis ... • Progressive symptoms ... Differential #Diagnosis #Rheumatology
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