21 results
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... less systemic symptoms ... anti-synthetase syndrome ... after 2 years of treatment ... Myositis #diagnosis #rheumatology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... thrombocythemia), Autoimmune ... disorders • Shear stress-induced ... Diagnosis #Management #treatment ... #hematology #differential
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Myasthenia Gravis is an autoimmune ... Bedside: ice pack test ... /Edrophonium test ... - Cogan sign ... - Peek sign 2.
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
meningitis), MCC CNS symptoms ... is a skin prick test ... Arthritis, AS Treatment ... diagnosis #management #signs ... #symptoms #rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... changes, stroke symptoms ... WBC >100k, + lab signs ... organ damage • Treatment ... diagnosis #management #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral infection, autoimmune ... CLL (older) • Autoimmune ... • Diagnostic Test ... Donath-Landsteiner test
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Sclerosis (MS) is an autoimmune-mediated ... • Or brainstem syndromes ... Signs and symptoms ... Multiple Sclerosis Treatment ... management #neurology #treatment
Anterior Non-necrotizing Scleritis - Slit Lamp Ocular Examination

This 57 yo WM reported to clinic complaining of
and had no other symptoms ... history of systemic autoimmune ... systemic workup and treatment ... ophthalmology #physicalexam ... #rheumatology #
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
virus or Group A Strep ... by neutrophilic autoimmune ... nephrotic/nephritic syndrome ... Pathophysiology #Diagnosis #Signs ... #Symptoms
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
adults in the west ... with no early symptoms ... Physical Exam/Signs ... microglobulin Treatment ... • Richter’s Syndrome