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diagnosis causes differential high management pathophysiology cardiology classification gitelman hypokalemia icucard k pharmacology treatment
Digoxin Pharmacology and Pathophysiology 1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
works by directly ... this pump, those sodium ... - Hyperkalemia ( ... , in states of hypokalemia ... (or low potassium
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
• Trauma/Crush injury ... : • Digoxin ... • Recent IV potassium ... - Tumor lysis syndrome ... #high #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
• Trauma/Crush injury ... : • Digoxin ... • Recent IV potassium ... - Tumor lysis syndrome ... #high #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Calcineurin inhibitors, Digoxin ... , rhabdo/crush injury ... reabsorption) Workup ... acidosis) • Low ... #nephrology #K
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
Digoxin and related ... neuromuscular injury ... Drug-associated: heparin, low-molecular-weight ... antiphospholipid syndrome ... Diagnosis #High #Potassium
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... alkalosis • Normal or low ... (renal potassium ... #diagnosis #nephrology
#ICUCard RENAL GFR 90-131 mL/min ((140-age)*Wt)/(72*Cr) Glomerular Filtration Rate (Cockcroft) CI Cr 90-131 mL/min (CrU * volume)/CrS Creatinine Clearance FENa 0.0-1.0 % ((U/P Na)/(U/P Cr))*100 Fractional Excretion of Na+ Na req mEq (125-Na)*0.6*Wt Required Sodium FE Urea
0.6*Wt Required Sodium ... Trans Tubular Potassium ... or spinal cord injury ... Distress Syndrome ... q10min (as needed) Digoxin
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