22 results
diagnosis hematology treatment syndrome disease antiphospholipid aps blood eular2019 guidelines oncology pathophysiology product reactions signs stills symptoms adult adultonset algorithm
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
mevalonate kinase deficiency ... • Ocular: uveitis ... Disease #diagnosis #management ... #treatment #rheumatology
Treatment of Thrombotic Thrombocytopenic Purpura (TTP) Diagnosis of TTP: • Rare and severe, ADAMTS13 deficiency • Autoimmune
severe, ADAMTS13 deficiency ... Thrombocytopenic #Purpura #management ... #treatment #rheumatology ... #hematology
Xeropthalmia: Pathogenesis and Ocular Manifestations Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
Pathogenesis and Ocular ... Decr Visual pigment ... with vitamin A deficiency
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
refractory lesions Ocular ... Syndrome #Treatment #management ... #pharmacology #rheumatology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management Vitamin C is required for hydroxylation of proline residues
Scurvy (Vitamin C Deficiency ... Diagnosis and Management ... mucocutaneous changes, ocular ... • Delusions Ocular ... : • Vitamin C deficiency
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
ulceration • Ocular ... spondyloarthritis • Ocular ... Leukemia, Lymphoma Ocular ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
anemia, GATA2 deficiency ... , CTLA4 deficiency ... Anemia #oncology #hematology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Cellular immune deficiency ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Algorithm for managing FVII deficiency. *Mild bleeding history includes minor epistaxis, menorrhagia, gastrointestinal bleeding, joint and soft
managing FVII deficiency ... nervous system and ocular ... #FVII #deficiency ... Factor7 #Algorithm #management ... #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
thrombopoietin deficiency ... causes #treatment #management ... #hematology
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