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diagnosis hepatology differential management causes transaminitis algorithm ascites hepatitis albumin blood classification hematology indications nephrology product reactions saag signs symptoms
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - ... • NAFLD • Cirrhosis ... Hepatopathy • Acute ... injury) • Ischemic ... Function #Tests #LFTs
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Liver Failure ( ... those with CLD (± cirrhosis ... Injury (DILI) ... #Failure #Cirrhosis
Table of Causes of Acute Liver Injury #Diagnosis #Hepatology #Acute #Liver #Injury #Causes #Differential #Incidence #Table #Failure
Table of Causes of Acute ... Liver Injury #Diagnosis ... #Hepatology #Acute ... #Liver #Injury ... Incidence #Table #Failure
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... Liver Failure ( ... injury < 26 weeks ... hepatitis: < 1 • Cirrhosis ... transaminitis #LFTs
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... Injury Transaminase ... > 20x normal - Acute ... CMV), Alcoholic cirrhosis ... #LFTs #transaminitis
Flapping tremors of Asterixis DDx - Decompensated cirrhosis or acute liver failure. - Renal failure /azotemia. - Respiratory failure with
Decompensated cirrhosis ... or acute liver ... failure ... - Renal failure ... - Respiratory failure
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 Clinical manifestations of acute liver failure Brain: Hepatic encephalopathy, Cerebral edema, Intracranial hypertension,
liver failure ... abnormalities Liver ... Subclinical myocardial injury ... lung injury, ... #liver #failure
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... Injury → liver ... failure 1) Hepatocellular ... Injury Differential ... Transaminitis #LFTs
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Liver Injury: ... Liver Injury: ... Liver Injury: ... hepatitis: < 1 • Cirrhosis
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Acute Kidney Injury ... Dehydration • Heart failure ... cardiorenal syndrome) • Liver ... failure (a.k.a. ... #Kidney #Injury
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