29 results
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Biliary Cirrhosis - Pathophysiology ... female-predominant disease ... of autoimmune disease ... T-cell mediated BEC injury ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Hepatocellular Liver Injury ... → liver test abnormalities ... Hemochromatosis, Wilson's disease ... HELLP, Celiac disease ... Differential #Diagnosis #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... dose dependent injury ... symptoms of liver disease ... differential #Diagnosis #Management ... gastroenterology #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
underlying liver disease ... Drug-Induced Liver Injury ... Hepatitis Procedures Management ... Failure #Cirrhosis #Hepatology ... gastroenterology #management
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Venoocclusive disease ... Hereditary: Wilson Disease ... of cholestatic disease ... extrahepatic source - Tests ... diagnosis #algorithm #hepatology
Vasospastic (Prinzmetal) Angina
Definition / Epidemiology:
 • Rest angina attributed to coronary artery vasospasm.
 • Patients often
Epidemiology: • Rest ... Pathophysiology: ... microvascular injury ... perform provocative tests ... cardiology #diagnosis #management
Non-alcoholic fatty liver disease algorithm.
 
For those patients with NAFLD or liver disease of unknown aetiology,
NAFLD or liver disease ... Second-line tests ... children, the text ... algorithm #Referral #Management ... #Hepatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
to local skin injury ... pathognomonic laboratory tests ... Positive pathergy test ... is a skin prick test ... Syndrome #diagnosis #management
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Diagnosis and Management ... ♀, ↑Age, ESRD Pathophysiology ... approach for post-test ... : Confirmatory test ... #Treatment #Hematology
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
Findings Compression/injury ... intervertebral disc disease ... Straight Leg Raise Test ... MeralgiaParesthetica #MSK #pathophysiology