10 results
Beta Lactam Antibiotic Classification

UPDATE 10/2018: meropenem-vaborbactam added

Penicillins, Cephalosporins, Monobactam, Carbapenems 

 - Dr. David Serota @serotavirus

#BetaLactams
Beta Lactam Antibiotic ... Classification ... Cephalosporins #Classification ... #Pharmacology #Classes
Lactic Acidosis - Overview and Pathophysiology
Lactic acid is an endogenous substrate for gluconeogenesis, that is constantly
Lactic Acidosis ... - Overview and Pathophysiology ... why LR does not cause ... differential #diagnosis #pathophysiology ... #classification
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Causes of Lactate ... The most common causes ... - Many other causes ... Causes of elevated ... Causes of Lactate
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... : CLASS 1 - Sodium ... duration: - CLASS ... #Pharmacology #Classification ... #Classes #pathophysiology
Hepatic Encephalopathy - Diagnosis and Management Summary
Definition:
 • Alteration in brain function manifested by neuropsychiatric symptoms
neuropsychiatric symptoms • Caused ... rule out other causes ... metabolized to lactic ... can be used in cases ... Encephalopathy #Grading #Classification
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Caused by splanchnic ... Pathophysiology: ... Exclude other AKI causes ... Classification: ... essential in all cases
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Vaughan Williams Classification ... : CLASS 1 - Sodium ... duration - CLASS ... #Pharmacology #Classification ... #Classes #pathophysiology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Collapse: • Pathophysiology ... and electrolyte losses ... Hyperventilation, Dizziness, Nausea ... Possible DIC - Mild lactic ... differential #diagnosis #causes
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Manifestations Causes ... also seen • Lactic ... beriberi #nutrition #pathophysiology
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Abnormal Osteoclasts cause ... Osteoarthritis • Lytic ... Skull expansion causes ... middle ear bones causes ... PagetsDisease #pathophysiology