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differential management neurology causes hepatology hepatopulmonary apml barre bronchiectasis cauda caudaequina cirrhosis classification comatose differentiation edema equina fungal guillain hematology
The Neurological Evaluation of a Comatose Patient Definition: • Coma: a state of unresponsiveness; the absence of
Differential Diagnosis ... Unresponsive wakefulness syndrome ... • Locked-in syndrome ... • Mutism Pathophysiology ... Glasgow Coma Scale (GCS
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
depressed deep tendon reflexes ... than one after symptom ... and sensitive tests ... the underlying pathophysiology ... and cauda equina TREATMENT
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
spine L1-L5 Symptoms ... Differential Diagnosis ... • Provocative Tests ... absent anal wink test ... axial T1 and T2 Treatment
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager ... Renal Syndromes ... ) Other tests: ... or serologies + symptoms ... #management #treatment
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... 10 minutes of rest ... ) on room air Treatment ... resolution of symptoms ... #treatment #hepatology
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
inflammation Symptoms ... • Mounier-Kuhn syndrome ... parenchyma Diagnosis ... mycobacteria Treatment ... #differential #diagnosis
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework High Altitude Pulmonary Edema: • Accumulation
- Differential Diagnosis ... blood-gas barrier ... 10,000 ft) • Symptoms ... - Dyspnea at rest ... #differential #diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... Imaging: CXR- pulmonary ... : >3 symptoms, or
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... glomerulonephritis) • Anti-GBM ... • Cogan Syndrome ... Presentation - Systemic Symptoms ... retinopathy Lab Tests
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Spasticity - Reflexes ... Bilateral signs and/or symptoms ... negative, MOG-IgG test ... Transverse Myelitis Treatment
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