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The Cell Cycle
The cell cycle is the series of tightly regulated steps that controls cell growth

through the G1/S checkpoint ... /S, S/G2, G2/M checkpoints ... the cell cycle checkpoints ... Ever had bad sunburn ... proliferation #TF #E2F #checkpoint

CT Lung Signs in Pulmonary Diseases - One Page Summary of Pulmonary Signs
- Air Crescent

Corona radiata (sunburst

Myocarditis

5 Principles of
Myocarditis:
1. Build clinical suspicion
2. Decide on EMBx
3. Manage acute cardiac injury
4. Manage chronic

Build clinical suspicion ... myocarditis Clinical ... anti-metabolite - Immune Checkpoint

Undifferentiated shock - Algorithm for the Evaluation of Hypotension. This process for the evaluation of hypotension

halting at evaluable checkpoints

Corona Radiata (Sunburst sign) on Chest CT
• SPN or mass, with spiculated and inegular margins

Corona Radiata (Sunburst ... Corona #Radiata #Sunburst ... diagnosis #radiology #clinical

Immune-related adverse events (irAE) of immune checkpoint inhibitors (ICI)

- By Antoine Briantais
Dr. Benjamin

irAE) of immune checkpoint

Pulmonary complications of targeted therapy
-Immune checkpoint inhibitors (e.g. pembrolizumab)
-Pneumonitis is uncommon (~5% of patients) but can

therapy -Immune checkpoint ... associated with a clinical ... #Clinical #Diagnosis

Check point inhibitors and Side Effects - Immune-related adverse events (IRAEs)

What are the side effects?
-

by stopping the checkpoint

Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
• Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,

Erdheim-Chester), Immune Checkpoint

VITAMINS Mnemonic for Acute / Subacute Peripheral Polyneuropathy

Vascular
Inflammatory: Amyloidosis, vasculitis (often more subacute/chronic)
Toxins: Nitrous oxide, chemo,

oxide, chemo, checkpoint

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