31 results
diagnosis rheumatology syndrome treatment hepatology hemophagocytic hlh lymphohistiocytosis neurology oncology vasculitis algorithm arthritis causes cholangitis classification dermatology erythematosus joint liver
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... immunofluorescence Immune ... involvement: Anti-GBM Disease ... Goodpasture's) Pauci-immune ... Glomerulonephritis #Vasculitis #differential
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
mimickers, Other auto-immune ... , Infectious diseases ... autoantibodies #signs #symptoms ... #mimickers #differential ... #rheumatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... ongoing ↑ LFTs or symptoms ... of liver disease ... Idiosyncratic #differential ... gastroenterology #hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... infiltration) Differential ... Liver #Pregnancy #hepatology ... #pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... that disrupts immune ... • Autoimmune diseases ... Others: Cellular immune ... Lymphohistiocytosis #diagnosis #management
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
Schedule: Why we immunize ... invade URT & via hematologic ... hemorrhagic rash; symptoms ... causes CNS and hematologic ... peds #pediatrics #pathophysiology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis Differential ... Presentation: Systemic Symptoms ... • Progressive symptoms ... #Diagnosis #Rheumatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... PBC Signs and Symptoms ... but elevated as disease ... bile ducts Differential ... diagnosis #workup #hepatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Eosinophilia and Systemic Symptoms ... Symptoms: • The ... Resolution > 15 days Differentials ... withdrawal • Mild disease ... #diagnosis #management
Optic Neuritis - Diagnosis and Management • Epidemiology: Female (75%), 18-50 years, caucasian • Symptoms: Moderate visual
Diagnosis and Management ... caucasian • Symptoms ... or other auto-immune ... diseases By ... #treatment #rheumatology
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