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diagnosis differential sle ana antibodies erythematosus systemic vasculitis antibody antineutrophil classification disease druginduced patterns polychondritis relapsing signs summary table tafro
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... ) • Systemic lupus ... scleroderma) - Anti-Scl ... cases • Sjögren syndrome ... antibodies #diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... context of other symptoms ... SLE), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... #patterns #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
- Summary Antinuclear ... block • Sjogren syndrome ... polymyositis overlap syndrome ... Summary #diagnosis #rheumatology ... #management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... constitutional symptoms ... Evolution: Chronic disease ... #sle #comparison ... #table #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
dermatomyositis, Sjogren syndrome ... lymphoma • Evans' syndrome ... lymphoproliferative syndrome ... Shrinking lung syndrome ... Erythematosus #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Mucocutaneous lymph node syndrome ... VASCULITIS: • Behçet ... Syndrome: - Recurrent ... • Cogan Syndrome ... differential #diagnosis #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome ... syndrome (Clinical ... adenopathy (PFAPA) syndrome ... #Syndrome #diagnosis ... #symptoms #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Mucocutaneous lymph node syndrome ... vasculitis • Behcet ... syndrome: Recurrent ... vasculitis • Cogan syndrome ... Differential #Diagnosis #Rheumatology
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
TAFRO TAFRO syndrome ... including systemic lupus ... , ANCA-associated ... and the systemic symptoms ... #rheumatology #
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
common • Sjogren’s syndrome ... • MAGIC syndrome ... • Vexus syndrome ... Nodosa, GCA, Sweet syndrome ... Polychondritis #rheumatology
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