10000 results
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings

 • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
Pathogenesis and Clinical ... Vit-D (1-25-OH2) synthesis ... signs #symptoms #diagnosis
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
Pathogenesis and clinical ... Death • Incr synthesis ... Refeeding #Syndrome #diagnosis
5-Oxoprolinuria
What is it:
 • Aka pyroglutamic acidosis, Intermediate in γ-glutamyl cycle
 • Amino acid transport and
and glutathione synthesis ... paracetamol ingestion Clinical ... flucloxacillin, vigabatrin Diagnosis ... high index of clinical ... Oxoprolinuria #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... : - Impaired synthesis ... #Coagulation #diagnosis
Antibiotic Classification by Mechanism of Action

Cell Wall Synthesis: 
Penicillins 
Cephalosporins 
Carbapenems 
Monobactams 
Beta-lactamase inhibitors
Glycopeptides 

 Protein
Action Cell Wall Synthesis ... Glycopeptides Protein Synthesis ... Folic Acid Synthesis ... Metronidazole mRNA Synthesis ... Recommended Text: Clinical
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Syndrome (SPS) - Diagnosis ... Clinical Manifestations ... Person Syndrome - Diagnosis ... involved in the synthesis ... Syndrome #SPS #Diagnosis
Synchysis Scintillans (cholesterolosis bulbi) on Slit Lamp Ocular Examination

Polychromatic crystals are observed in the anterior chamber
Synchysis Scintillans ... @oftalmopo #Synchysis ... #PhysicalExam #clinical
Heme Synthesis Pathway
Enzymes
1. ALA Synthase
2. ALA Dehydratase
3. Porphobilinogen deaminase
4. UP Ill Synthase
5. UP Ill Decarboxylase
6. Coproporphyrinogen
Heme Synthesis Pathway ... JamesCaoMD #Heme #Synthesis ... pathophysiology #diagnosis
Antibiotics - Mechanisms and Sites of Action 

Inhibit Cell Wall Synthesis or Function 
- Beta Lactams,
Inhibit Cell Wall Synthesis ... Inhibit Protein Synthesis ... Inhibit Protein Synthesis ... Inhibit Nucleic Acid Synthesis ... Inhibits Folate Synthesis
Functions of the Liver

Storage 
Degradation 
Metabolism 
Synthesis 

#Pathophysiology #Functions #Liver #Hepatology #Synthesis #Storage #Metabolism
Metabolism Synthesis ... Liver #Hepatology #Synthesis