9499 results
5-Oxoprolinuria
What is it:
 • Aka pyroglutamic acidosis, Intermediate in γ-glutamyl cycle
 • Amino acid transport and
and glutathione synthesis ... paracetamol ingestion Clinical ... high index of clinical ... Oxoprolinuria #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... : - Impaired synthesis ... causes #treatment #management
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... Clinical Manifestations ... involved in the synthesis ... SPS #Diagnosis #Management
Antibiotic Classification by Mechanism of Action

Cell Wall Synthesis: 
Penicillins 
Cephalosporins 
Carbapenems 
Monobactams 
Beta-lactamase inhibitors
Glycopeptides 

 Protein
Action Cell Wall Synthesis ... Glycopeptides Protein Synthesis ... Folic Acid Synthesis ... Metronidazole mRNA Synthesis ... Recommended Text: Clinical
Synchysis Scintillans (cholesterolosis bulbi) on Slit Lamp Ocular Examination

Polychromatic crystals are observed in the anterior chamber
Synchysis Scintillans ... @oftalmopo #Synchysis ... #PhysicalExam #clinical
Antibiotics - Mechanisms and Sites of Action 

Inhibit Cell Wall Synthesis or Function 
- Beta Lactams,
Inhibit Cell Wall Synthesis ... Inhibit Protein Synthesis ... Inhibit Protein Synthesis ... Inhibit Nucleic Acid Synthesis ... Inhibits Folate Synthesis
Pharmaceutical Management of Hyperthyroidism / Thyroid Storm
Beta-Blockers 
• Decreases sympathetic hyperactivity 
• Partially blocks peripheral conversion
Pharmaceutical Management ... PTU) • Blocks synthesis ... Methimazole • Blocks synthesis ... #ThyroidStorm #Management
Functions of the Liver

Storage 
Degradation 
Metabolism 
Synthesis 

#Pathophysiology #Functions #Liver #Hepatology #Synthesis #Storage #Metabolism
Metabolism Synthesis ... Liver #Hepatology #Synthesis
The Pathway of Heme Synthesis, Showing Pathway Intermediates and End-Product Regulation by Heme #Pathophys #Honc #Heme
Pathway of Heme Synthesis ... Pathophys #Honc #Heme #Synthesis
Protein Losing Enteropathy
Clinical Presentation:
 • Volume overload: Peripheral edema, pleural effusion or ascites.
 • Gl symptoms
Losing Enteropathy Clinical ... or inadequate synthesis ... Enteropathy #diagnosis #management