11 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... lymphohistiocytosis (HLH ... Petechial or purpuric rash ... #Diagnosis #Management ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... : HLH signs and ... Diagnosis via genetic ... #management #treatment ... #hematology
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
staphylococcal scalded skin syndrome ... and toxic shock syndrome ... erythematous rash ... #Diagnosis #Dermatology ... #Erythematous #Rash
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... Episcleritis Signs ... , breast CA - Hematologic ... #diagnosis #dermatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... hyperviscosity syndrome ... WBC >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome ... syndrome, a search ... Macrophage Activation Syndrome ... Presentation • Common Signs ... #Management #Hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
extensive skin rash ... Criteria for Diagnosis ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis ... #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
common in Asia • HLA-B51 ... ) Differential Diagnosis ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Vancomycin induced Leukocytoclastic Vasculitis (LCV) of the Hand
70 M vertebral osteomyelitis on vancomycin and cefepime for
diffuse palpable rash ... Diagnosis? ... Churg-Strauss syndrome ... Hand #skinrash #dermatology ... #clinical #photo
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
- Differential Diagnosis ... , Loose anagen syndrome ... Examination: • Signs ... Prolactin, FSH, LH ... #dermatology #Hairloss