16 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Clinically Relevant HES ... #HES #Hematology ... #eosinophilia # ... eosinophils #diagnosis ... #management #algorithm
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... (HES) - Diagnosis ... and Management ... #HES #eosinophilia ... #diagnosis #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... 1,500 cells/µL Workup ... organ-specific signs ... #Differential #diagnosis ... #hematology #eosinophilia
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
Algorithm for workup ... TTP/HUS indicates ... hemolytic uremic syndrome ... thrombocytopenia, Hematology ... 2012, p 193 #Diagnosis
Eosinophilic Gastroenteritis: Treatment Options Based on Severity of the Disease
Mild:
 • Trial of PPI
 • Trial
Eosinophilic Gastroenteritis ... + Concern for HES ... : • Hematology ... • Additional diagnostic ... Gastroenteritis #Treatment #management
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... and Differential Diagnosis ... clinical context and signs ... Interstitial nephritis: eosinophilia ... pressure • TTP / HUS
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Criteria for Diagnosis ... Exanthematous Pustulosis Management ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis ... #management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Agent Orange or Hep ... Physical Exam/Signs ... • Richter’s Syndrome ... #workup #oncology ... #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... hyperviscosity syndrome ... WBC >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... : HLH signs and ... Diagnosis via genetic ... #management #treatment ... #hematology