98 results
Steroid Synthesis Pathway

Dr. Caoimhe Costigan @CaoimheCostigan

#Steroid #Synthesis #pathophysiology #algorithm #endocrinology
Steroid Synthesis ... CaoimheCostigan #Steroid #Synthesis ... #pathophysiology ... #algorithm #endocrinology
Insulin and Glucagon Pathophysiology
Insulin: 
 • Glucose utilization (Glycolysis)
 • Glucose storage (Glycogenesis)
 • Fat synthesis
Insulin and Glucagon Pathophysiology ... Glycogenesis) • Fat synthesis ... tissues Glucagon Actions ... : • Glucose synthesis ... Insulin #Glucagon #Pathophysiology
Mechanism of Action of Bile Acid Sequestrants
Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Mechanism of Action ... Hepatic Bile Acid Synthesis ... sequestration #pathophysiology
Renal Effect of NSAIDs Inhibition of Prostaglandin Synthesis

 - Renal disease, Cardiovascular disease -> Decreased renal
Prostaglandin Synthesis ... prostaglandin synthesis ... , leaving actions ... #Pharmacology #Pathophysiology
Vitamin deficiency causes clinical disease
Vitamin C deficiency causes scurvy.  Vitamin C is important for the
Vitamin deficiency causes ... Vitamin C deficiency causes ... required for the synthesis ... #Pathophysiology ... Catecholamine #Synthesis
Vitamin D Metabolism
Fat-soluble vitamin
Sources: dermal synthesis and food (dairy products, fish)
Active form: calcitriol (1,25-OH Vitamin D)
Main
Sources: dermal synthesis ... products, fish) Active ... endocrinology #pathophysiology
Tranexamic Acid: Mechanism of Action
 - TXA is an anti-fibrinolytic
 - TXA is a synthetic analog
: Mechanism of Action ... anti-fibrinolytic - TXA is a synthetic ... Tranexamic #Acid #pathophysiology
Antiemetics and Vomiting

#Pathophysiology #Antiemetics #Locations #Action #Pathways #Nausea #Chemotherapy #TriggerZone #CTZ
and Vomiting #Pathophysiology ... Antiemetics #Locations #Action ... #Pathways #Nausea
Shock - Pathophysiology 
Inadequate tissue perfusion to meet O2, nutrient requirements
1. Distributive Shock
2. Hypovolemic Shock
3. Cardiogenic
Shock - Pathophysiology ... Shock #Shock #Pathophysiology ... differential #diagnosis #algorithm ... #causes
Fever - Pyrogen Pathophysiology

EXOGENOUS PYROGEN
 • Bacteria: Lipopolysaccharide components, peptidoglycans and muramyl peptide derivatives, Toxins
 •
Fever - Pyrogen Pathophysiology ... macrophages) → Synthesis ... vasculature via: • Active ... Pyrogen → Induce synthesis ... Fever #Fever #Pathophysiology