36 results
Fever - Pyrogen Pathophysiology

EXOGENOUS PYROGEN
 • Bacteria: Lipopolysaccharide components, peptidoglycans and muramyl peptide derivatives, Toxins
 •
Pathophysiology ... macrophages) → Synthesis ... vasculature via: • Active ... Pyrogen → Induce synthesis ... #Fever #Pathophysiology
Insulin and Glucagon Pathophysiology
Insulin: 
 • Glucose utilization (Glycolysis)
 • Glucose storage (Glycogenesis)
 • Fat synthesis
Insulin and Glucagon Pathophysiology ... Glycogenesis) • Fat synthesis ... tissues Glucagon Actions ... : • Glucose synthesis ... Insulin #Glucagon #Pathophysiology
Steroid Synthesis Pathway

Dr. Caoimhe Costigan @CaoimheCostigan

#Steroid #Synthesis #pathophysiology #algorithm #endocrinology
Steroid Synthesis ... CaoimheCostigan #Steroid #Synthesis ... #pathophysiology ... #algorithm #endocrinology
Mechanism of Action of Bile Acid Sequestrants
Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Mechanism of Action ... Hepatic Bile Acid Synthesis ... sequestration #pathophysiology
Renal Effect of NSAIDs Inhibition of Prostaglandin Synthesis

 - Renal disease, Cardiovascular disease -> Decreased renal
Prostaglandin Synthesis ... prostaglandin synthesis ... , leaving actions ... #Pharmacology #Pathophysiology
Vitamin D Metabolism
Fat-soluble vitamin
Sources: dermal synthesis and food (dairy products, fish)
Active form: calcitriol (1,25-OH Vitamin D)
Main
Sources: dermal synthesis ... products, fish) Active ... endocrinology #pathophysiology
Tranexamic Acid: Mechanism of Action
 - TXA is an anti-fibrinolytic
 - TXA is a synthetic analog
: Mechanism of Action ... anti-fibrinolytic - TXA is a synthetic ... Tranexamic #Acid #pathophysiology
Rigors And Bacteremia - Overview

• Rigors are a response to the release of cytokines and prostaglandins
hypothalamus → fever ... PATHOPHYSIOLOGY: ... Macrophages → Synthesis ... vasculature via: • Active ... pyrogen induces synthesis
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
Erythematous Rashes - THE ALGORITHMIC ... or absence of fever ... an anaphylactic reaction ... or an exposure reaction ... Erythematous #Rash #Algorithm
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic Algorithm ... Pathophysiology ... - Pathophysiology ... instability - New-onset fever ... Color #Targetoid #Algorithm