582 results
Steroid Synthesis Pathway

Dr. Caoimhe Costigan @CaoimheCostigan

#Steroid #Synthesis #pathophysiology #algorithm #endocrinology
Steroid Synthesis ... CaoimheCostigan #Steroid #Synthesis ... pathophysiology #algorithm #endocrinology
Steroid Synthesis Pathway

(OH, hydroxy; HSD, hydroxysteroid dehydrogenase; DHEA, dehydroepiandrosterone; pink, common enzymes affecting CAH, purple –
Steroid Synthesis ... CaoimheCostigan #Steroid #Synthesis ... pathophysiology #endocrinology
Overview of hypothalamus and pituitary hormones and their regulation.

#hypothalamus #pituitary #endocrinology #Hormones #diagnosis #algorithm
Overview of hypothalamus ... hypothalamus #pituitary #endocrinology
Insulin and Glucagon Pathophysiology
Insulin: 
 • Glucose utilization (Glycolysis)
 • Glucose storage (Glycogenesis)
 • Fat synthesis
Glycogenesis) • Fat synthesis ... Lipogenesis) • Protein synthesis ... Actions: • Glucose synthesis ... Pathophysiology #endocrinology
Vitamin D Metabolism
Fat-soluble vitamin
Sources: dermal synthesis and food (dairy products, fish)
Active form: calcitriol (1,25-OH Vitamin D)
Main
Sources: dermal synthesis ... VitaminD #Metabolism #endocrinology
Antifungal Azoles - Antibiotics Class Overview

Mechanism:  inhibit ergosterol synthesis (important component of fungal cell membranes)
Antibiotics Class Overview ... inhibit ergosterol synthesis ... Antibiotics #Review #Overview
Synercid (Quinupristin/Dalfopristin) (IV) - Antibiotics Class Overview

Mechanism: “Streptogramins”– inhibits sequential steps in ribosomal synthesis
Spectrum: covers MRSA
Antibiotics Class Overview ... steps in ribosomal synthesis ... Antibiotics #Review #Overview
Pharmaceutical Management of Hyperthyroidism / Thyroid Storm
Beta-Blockers 
• Decreases sympathetic hyperactivity 
• Partially blocks peripheral conversion
PTU) • Blocks synthesis ... Methimazole • Blocks synthesis ... Administer only after synthetic
Antibiotic Classification by Mechanism of Action

Cell Wall Synthesis: 
Penicillins 
Cephalosporins 
Carbapenems 
Monobactams 
Beta-lactamase inhibitors
Glycopeptides 

 Protein
Action Cell Wall Synthesis ... Glycopeptides Protein Synthesis ... Folic Acid Synthesis ... Metronidazole mRNA Synthesis
Antibiotics - Mechanisms and Sites of Action 

Inhibit Cell Wall Synthesis or Function 
- Beta Lactams,
Inhibit Cell Wall Synthesis ... Inhibit Protein Synthesis ... Inhibit Protein Synthesis ... Inhibit Nucleic Acid Synthesis ... Inhibits Folate Synthesis