3473 results
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... : - Impaired synthesis ... causes #treatment #management
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... Person Syndrome Pathophysiology ... involved in the synthesis ... SPS #Diagnosis #Management
Functions of the Liver

Storage 
Degradation 
Metabolism 
Synthesis 

#Pathophysiology #Functions #Liver #Hepatology #Synthesis #Storage #Metabolism
Metabolism Synthesis ... #Pathophysiology ... Liver #Hepatology #Synthesis
SEX HORMONE SYNTHESIS, REGULATION, AND FUNCTION - Steroidogenesis

#Pathophysiology #Steroidogenesis #Androgens #Glucocorticoids #Mineralocorticoid
SEX HORMONE SYNTHESIS ... Steroidogenesis #Pathophysiology
Pharmaceutical Management of Hyperthyroidism / Thyroid Storm
Beta-Blockers 
• Decreases sympathetic hyperactivity 
• Partially blocks peripheral conversion
Pharmaceutical Management ... PTU) • Blocks synthesis ... Methimazole • Blocks synthesis ... Administer only after synthetic ... #ThyroidStorm #Management
Steroid Synthesis Pathway

(OH, hydroxy; HSD, hydroxysteroid dehydrogenase; DHEA, dehydroepiandrosterone; pink, common enzymes affecting CAH, purple –
Steroid Synthesis ... CaoimheCostigan #Steroid #Synthesis ... Pathway #metabolism #pathophysiology
Steroid Synthesis Pathway

Dr. Caoimhe Costigan @CaoimheCostigan

#Steroid #Synthesis #pathophysiology #algorithm #endocrinology
Steroid Synthesis ... CaoimheCostigan #Steroid #Synthesis ... #pathophysiology
Heme Synthesis Pathway
Enzymes
1. ALA Synthase
2. ALA Dehydratase
3. Porphobilinogen deaminase
4. UP Ill Synthase
5. UP Ill Decarboxylase
6. Coproporphyrinogen
Heme Synthesis Pathway ... JamesCaoMD #Heme #Synthesis ... #Pathway #pathophysiology
Insulin and Glucagon Pathophysiology
Insulin: 
 • Glucose utilization (Glycolysis)
 • Glucose storage (Glycogenesis)
 • Fat synthesis
Insulin and Glucagon Pathophysiology ... Glycogenesis) • Fat synthesis ... Lipogenesis) • Protein synthesis ... Actions: • Glucose synthesis ... Insulin #Glucagon #Pathophysiology
Arachidonic acid pathway and drugs which affect it.

#Pharmacology #Pathophysiology #ArachidonicAcid #Pathways #COX #Prostaglandins #Prostacyclins #Leukotrienes #Synthesis

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#Pharmacology #Pathophysiology ... #Leukotrienes #Synthesis