16 results
Immune Checkpoint Inhibitor Toxicity

Main Toxicities: Colitis,  
Pneumonitis, Skin adverse events, Endocrine dysfunction, 
Hepatitis,  
Myocarditis,
Checkpoint Inhibitor Toxicity ... Incidence, Symptoms ... Complications and Treatment ... Table #Diagnosis #Pharmacology ... #Oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
site in lymphatic system ... with lymphatic system ... pattern of spread, B symptoms ... Responsive to Treatment ... pathophysiology #Hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
rendering the immune system ... with no early symptoms ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Diagnosis: >3 symptoms ... initiation • Differential ... Renal Failure Treatment ... #oncology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
very remarkable w/differential ... of the steroid treatment ... Treatment of GCA ... them, but urgent rheumatology ... Temporal #Signs #Symptoms
Premature Ventricular Complexes (PVC's) - Summary Framework

Why PVCs?  Can be the first manifestation of cardiac
Substances • Digoxin toxicity ... Symptoms: • ... may not occur Differential ... more intensive treatment ... #cardiology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome Systemic ... meningitis), MCC CNS symptoms ... Behcet disease) Differential ... Arthritis, AS Treatment ... #rheumatology #
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
hematopoietic stem ... aplastic anemia Treatment ... • Improve the symptoms ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
bone marrow or stem ... Neurological symptoms ... Reversible course Differential ... Medication/Drug toxicity ... epilepticus Treatment
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
reconstituted immune system ... Confusion, visual symptoms ... Leishmaniasis Differential ... Drug reaction/ART toxicity ... Inflammatory #Syndrome #Differential