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Thyroid Function Tests (TFTs) and Interpretation

 • TSH, Free T4, Free T3
 • T3 Uptake
 •
Thyroid Function ... Free T4, Free T3 ... • T3 Uptake ... FTI) • Reverse T3 ... DharSaty #Thyroid #Function
Thyroid Function Test Interpretation Table

TSH, Free T4, Free T3 and Associated Condition
#Diagnosis #Endocrinology #Hyperthyroid #Hypothyroid #Function
Thyroid Function ... Free T4, Free T3 ... #Hypothyroid #Function
Approach to Thyroid Function Tests in the Evaluation of Hyperthyroidism
 • Low TSH, Low normal T4
Approach to Thyroid Function ... normal T4 +/- T3 ... of pregnancy, critical ... TSH, high T4 +/- T3 ... TSH, high T4 +/- T3
Laboratory Evaluation of Patients for Thyroid Disease 
Hyperthyroidism:
 • Graves disease - TSH low; free T4
in some cases, T3 ... low; free T4 and T3 ... low; free T4 and T3 ... low; free T4 and T3 ... low; free T4 and T3
Approach to the Diagnosis of Hyperthyroidism - Differential Diagnosis and Workup Algorithm

 • Secondary Hyperthyroidism (↑↔TSH,
↑↔TSH, ↑Total T3 ... (↓TSH, ↔Total T3 ... (↓TSH, ↑Total T3 ... (↔TSH, ↔Total T3
Pharmaceutical Management of Hyperthyroidism / Thyroid Storm
Beta-Blockers 
• Decreases sympathetic hyperactivity 
• Partially blocks peripheral conversion
conversion of T4 to T3 ... conversion of T4 to T3 ... conversion ofT4 to T3
Algorithm for the diagnostic workup of hyperthyroidism. (T3 = triiodothyronine; T4 = thyroxine; TSH = thyroid-stimulating
(T3 = triiodothyronine
Hyperthyroidism Overview

Clinical Manifestation of Hyperthyroidism:
 • Fatigue
 • Weight loss
 • Heat intolerance
 • Depression, nervousness
Hyperthyroidism Overview Clinical ... thyrotoxicosis • T3 ... TSH • ↑ Total T3 ... ↑ FT4 and/or ↑ T3 ... : Reduce T4 -> T3
Thyroid Function Pathway 

Hypothyroidism is a very common condition! Here's a repost of the pathway that
Thyroid Function ... stimulate more T4/T3
Abnormal Serum TSH - Differential Diagnosis Algorithm
Increased TSH
 • Hypothyroidism
 • Sub-clinical Hypothyroidism
 • Recovery from
Hypothyroidism • Sub-clinical ... Illness • Sub-Clinical ... Thyrotoxicosis • T3