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diagnosis differential endocrinology dermatology generalized pruritus systemic alopecia anemia cardiology dyslipidemia focal gynecomastia hairloss hematology htn hyperlipidemia hypertension hypothyroid interpretation
Approach to Thyroid Function Tests in the Evaluation of Hyperthyroidism • Low TSH, Low normal T4
Approach to Thyroid ... +/- T3 → Primary ... symmetrically enlarged thyroid ... T3 → Central (secondary ... #algorithm #diagnosis
Laboratory Evaluation of Patients for Thyroid Disease Hyperthyroidism: • Graves disease - TSH low; free T4
Disease Hyperthyroidism ... high; in some cases ... iodine uptake Hypothyroidism ... disease course #hypothyroid ... #hyperthyroid #
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
• Insomnia Primary ... goiter • Toxic diffuse ... thyroiditis Secondary ... T3 • ↑ Free T4 ... #causes #diagnosis
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential Diagnosis Algorithm ... Causes == Primary ... /uremia TSH & T4 ... #secondary #systemic ... #causes
Abnormal Lipid Profiles - Differential Diagnosis Algorithm Increased Cholesterol and Triglycerides - Genetic Causes
Abnormal Lipid Profiles ... Differential Diagnosis Algorithm ... Diabetes • Hypothyroidism ... Deficiency • Primary ... Hypothyroid
Primary and Secondary Causes of Hypertension - Differential Diagnosis Algorithm Primary (Essential) (95%) - Onset between age
Primary and Secondary ... Differential Diagnosis Algorithm ... Mislabelled - Repeatedly normal ... hypertension) • Hypothyroidism ... Differential #Diagnosis #Algorithm
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Differential Diagnosis Algorithm ... • Hyperthyroidism ... contraceptives • Hyperthyroid ... decalvans - Secondary ... #causes
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Reticulocytosis • Primary ... Hypersplenism • Secondary ... Cancer • Hypothyroid ... #Causes #Hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary ... /uremia TSH & T4 ... : • Hypothyroidism ... #Pruritus #secondary ... #causes
Gynecomastia - Differential Diagnosis Algorithm No Testicular Mass on Ultrasound • Adrenal Neoplasm • Increased Extraglomerular Aromatase
Tumor Increased T4 ... Decreased TSH • Hyperthyroidism ... T4 and TSH • ... • Non-Tumor Secondary ... #causes #endocrinology
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