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diagnosis endocrinology differential management dequervains dyslipidemia hashimotos hashitoxicosis hyperlipidemia hypothyroid interpretation lipidprofiles pathophysiology pmr polymyalgia primarycare rheumatica rheumatology signs subacute
Laboratory Evaluation of Patients for Thyroid Disease Hyperthyroidism: • Graves disease - TSH low; free T4
Disease Hyperthyroidism ... high; in some cases ... iodine uptake Hypothyroidism ... disease course #hypothyroid ... #hyperthyroid #
Approach to Thyroid Function Tests in the Evaluation of Hyperthyroidism • Low TSH, Low normal T4
Approach to Thyroid ... T4 → Possibly Central ... +/- T3 → Primary ... symmetrically enlarged thyroid ... #algorithm #diagnosis
Hashitoxicosis ‘Leakage’ symptoms of active Hashimoto’s disease - Hashitoxicosis (Htx) can occur during the initial hyperthyroid stage in
Hashitoxicosis ‘Leakage’ symptoms ... during the initial hyperthyroid ... thyroiditis that causes ... Diffuse infiltration ... ‘Leakage’ symptoms
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
• Insomnia Primary ... goiter • Toxic diffuse ... T3 • ↑ Free T4 ... #causes #diagnosis ... endocrinology #signs #symptoms
Abnormal Lipid Profiles - Differential Diagnosis Algorithm Increased Cholesterol and Triglycerides - Genetic Causes
Abnormal Lipid Profiles ... Differential Diagnosis Algorithm ... Diabetes • Hypothyroidism ... Deficiency • Primary ... • Hypothyroid
Subacute Thyroiditis Also known as: de Quervain’s thyroiditis, granulomatous thyroiditis, or viral thyroiditis What? Postviral inflammatory process caused by
inflammatory process caused ... returns to normal ... after onset Causes ... levels, ↓ TSH (2) Hypothyroid ... phase: ↓ T4 and
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary WHAT? • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
disease of unknown cause ... degenerative diseases, hypothyroidism ... DIAGNOSIS: • PMR primarily ... creatine kinase, and thyroid-stimulating ... generally are normal
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